Fatih M Uckun Selected Research

3'-azidothymidine 5'-(p-methoxyphenyl methoxyalaninyl phosphate)

1/2004	In vitro and in vivo pharmacokinetic features and metabolism of the novel cytotoxic nucleoside analog 3'-azidothymidine 5'-[p-methoxyphenyl methoxyalaninyl phosphate] (Compound 003).
1/2004	Anti-cancer activity profile of 3'-azidothymidine 5'-[p-methoxyphenyl methoxyalaninyl phosphate] (Compound 003), a novel nucleoside analog.

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Fatih M Uckun Research Topics

Disease

30	Neoplasms (Cancer) 01/2021 - 12/2002
23	Leukemia 01/2022 - 04/2002
19	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2018 - 02/2002
13	Acquired Immunodeficiency Syndrome (AIDS) 04/2012 - 11/2002
11	Lymphoma (Lymphomas) 01/2022 - 05/2002
10	Inflammation (Inflammations) 02/2016 - 12/2003
7	Infections 01/2021 - 06/2002
6	Breast Neoplasms (Breast Cancer) 01/2020 - 12/2002
5	COVID-19 01/2021 - 01/2020
5	Multiple Myeloma 01/2021 - 12/2002
3	Cytokine Release Syndrome 10/2021 - 01/2021
3	Sepsis (Septicemia) 09/2021 - 02/2016
3	Glioblastoma (Glioblastoma Multiforme) 11/2019 - 12/2002
3	Peritonitis 02/2008 - 06/2002
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 03/2005 - 03/2003
3	Hypersensitivity (Allergy) 03/2004 - 01/2002
2	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2022 - 01/2010
2	Hematologic Neoplasms (Hematological Malignancy) 01/2022 - 01/2021
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2021 - 12/2019
2	Disease Progression 01/2021 - 01/2021
2	Philadelphia Chromosome 01/2018 - 12/2013
2	Pancreatic Neoplasms (Pancreatic Cancer) 04/2016 - 08/2015
2	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 01/2010 - 01/2007
2	Sunburn 01/2010 - 08/2007
2	Colitis 02/2008 - 08/2007
2	Cellulitis 02/2008 - 08/2007
2	HIV Infections (HIV Infection) 07/2005 - 01/2004
2	Graft vs Host Disease (Graft-Versus-Host Disease) 09/2004 - 06/2002
2	Viral Hemorrhagic Fevers (Viral Hemorrhagic Fever) 06/2004 - 01/2004
2	Thromboembolism 01/2004 - 09/2003
2	Ovarian Neoplasms (Ovarian Cancer) 01/2003 - 12/2002
2	Testicular Neoplasms (Testicular Cancer) 01/2003 - 12/2002
1	Burns 01/2022
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 10/2021
1	Malaria 01/2021
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2020
1	Virus Diseases (Viral Diseases) 01/2020

Drug/Important Bio-Agent (IBA)

23	Pharmaceutical PreparationsIBA 09/2021 - 01/2004
10	Agammaglobulinaemia Tyrosine KinaseIBA 01/2022 - 06/2003
10	Proteins (Proteins, Gene)FDA Link 01/2021 - 04/2002
10	Janus Kinase 3IBA 01/2010 - 06/2002
9	WHI P131IBA 01/2020 - 06/2002
6	Phosphotransferases (Kinase)IBA 01/2020 - 01/2004
6	stampidineIBA 04/2012 - 11/2002
6	LFM A13IBA 12/2007 - 05/2002
6	NucleosidesIBA 08/2006 - 03/2003
5	Tyrosine (L-Tyrosine)FDA Link 01/2020 - 01/2004
5	Anti-Infective Agents (Microbicides)IBA 03/2012 - 12/2002
5	6- dihydro- 3'- azidothymidine- 5'- (p- bromophenyl) methoxyalaninyl phosphate 5-bromo-6-methoxy-5IBA 04/2008 - 11/2003
4	Syk KinaseIBA 06/2015 - 02/2010
4	Phosphates (Orthophosphate)IBA 01/2005 - 11/2002
3	Biomarkers (Surrogate Marker)IBA 10/2021 - 12/2007
3	CytokinesIBA 01/2021 - 01/2011
3	Paclitaxel (Taxol)FDA LinkGeneric 01/2020 - 01/2007
3	ErbB Receptors (EGF Receptor)IBA 01/2020 - 01/2007
3	Small Interfering RNA (siRNA)IBA 02/2016 - 05/2013
3	Biological ProductsIBA 12/2013 - 04/2002
3	HI 443IBA 03/2012 - 12/2004
3	Contraceptive Agents (Contraceptives)IBA 04/2008 - 01/2003
3	Zidovudine (Retrovir)FDA LinkGeneric 01/2005 - 01/2004
3	Messenger RNA (mRNA)IBA 09/2003 - 04/2002
2	COVID-19 VaccinesIBA 01/2022 - 01/2021
2	ascorbic acid, magnesium sulfate heptahydrate, cyanocobalamin, thiamine hydrochloride, riboflavin 5' phosphate, niacinamide, pyridoxine hydrochloride, and calcium D-pantothenate drug combinationIBA 09/2021 - 01/2020
2	Interleukin-3 Receptor alpha SubunitIBA 01/2021 - 01/2021
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020 - 06/2002
2	Diphosphates (Pyrophosphates)IBA 12/2019 - 01/2005
2	RNA (Ribonucleic Acid)IBA 11/2019 - 07/2015
2	Peptides (Polypeptides)IBA 02/2016 - 12/2014
2	Transcription Factors (Transcription Factor)IBA 01/2013 - 07/2002
2	VanadiumIBA 12/2007 - 04/2004
2	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 08/2006 - 06/2003
2	DNA (Deoxyribonucleic Acid)IBA 08/2006 - 04/2002
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 03/2006 - 01/2004
2	Antiviral Agents (Antivirals)IBA 07/2005 - 11/2002
2	3'-azidothymidine 5'-(p-methoxyphenyl methoxyalaninyl phosphate)IBA 01/2004 - 01/2004
2	Methotrexate (Mexate)FDA LinkGeneric 09/2003 - 06/2002
2	LeukotrienesIBA 02/2003 - 06/2002
1	AntibodiesIBA 01/2022
1	brassIBA 01/2022
1	Saline SolutionIBA 01/2022
1	insulin receptor-related receptor (IRR)IBA 08/2021
1	artemisinin (artemisinine)IBA 01/2021
1	AntigensIBA 01/2021
1	VaccinesIBA 01/2021
1	ADP-ribosyl Cyclase 1IBA 01/2021
1	bis(3- bis(4- chlorophenyl)methyl- 4- dimethylaminophenyl)amineIBA 01/2021
1	Bispecific AntibodiesIBA 01/2021
1	Transforming Growth Factor beta (TGF-beta)IBA 01/2020
1	AntioxidantsIBA 01/2020
1	polypeptide 1 70kD ribosomal protein S6 kinaseIBA 01/2020
1	Interleukin-6 (Interleukin 6)IBA 01/2020

Therapy/Procedure

16	Therapeutics 01/2022 - 02/2002
10	Drug Therapy (Chemotherapy) 01/2021 - 05/2002
3	Bone Marrow Transplantation (Transplantation, Bone Marrow) 09/2004 - 06/2002
2	Chemoprevention 01/2020 - 01/2010
2	Precision Medicine 04/2016 - 08/2015
2	Intravaginal Administration 04/2008 - 12/2007
2	Lasers (Laser) 12/2007 - 01/2003
1	Intraperitoneal Injections 01/2022
1	Investigational Therapies (Experimental Therapy) 01/2020